Monthly Archives: April 2010

Image Caption: This is a canine retina, injected with an AAV2/5 carrying the GRK1 promoter and the GFP gene. A red antibody that specifically identifies cones was used to label this class of photoreceptor cells, and confirm that GFP targeted … Continue reading →

Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by … Continue reading →

In trying to plant his tomatoes upside down, Terry Dickson ended up with his shirt and shoes full of dirt. We offer instead this insightful correspondence from Bubba Gene Hightower, mayor of Pond Scoggin, Ga. Dear Mr. Dickerson, I hope … Continue reading →

Ceregene, Inc., a biopharmaceutical company, announced that enrollment is proceeding in a new Phase 1/2 clinical study evaluating CERE-120, a gene therapy product which delivers the neurotrophic factor neurturin, to dying neurons in Parkinson’s disease patients. This new clinical study … Continue reading →

Findings describe a biodegradable gene therapy nanotechnology that can silence genes more stably. (Source: Cancer Research)

Findings describe a novel cell-based technology for delivery of a proapoptotic cancer gene therapy. (Source: Cancer Research)

(University of Pennsylvania) Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited … Continue reading →

Authors: J M Dadgari, R E Moore, K A Louie, T D Lee & M McMillan (Source: Gene Therapy)

Authors: G D Trobridge & H-P Kiem (Source: Gene Therapy) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – updated hourly from thousands of authoritative health and news sources.

rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters Gene Therapy advance online publication, April 29, 2010. doi:10.1038/gt.2010.56 Authors: W A Beltran, S L Boye, S E Boye, V A Chiodo, A S Lewin, W W Hauswirth & … Continue reading →

Authors: C D Kaufman, R C Geiger & D A Dean (Source: Gene Therapy)

Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype Gene Therapy advance online publication, April 29, 2010. doi:10.1038/gt.2010.59 Authors: P Neeson, A Shin, K M Tainton, P Guru, H … Continue reading →

Authors: T Aoki, H Kataoka, M Nishimura, R Ishibashi, R Morishita & S Miyamoto (Source: Gene Therapy)