CAT | Gene therapy
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CMS Approves Clinical Study Of Genetic Test To Predict Patient Response To Leading Anticoagulant Drug Warfarin
0 Comments | Posted by admin in Gene therapy
Iverson Genetic Diagnostics announced the company has received approval from CMS to conduct a WARFARIN Clinical Study. The two-year study will assess the impact of genetic information in calculating doses and the changes in the rate of adverse events when initiating Warfarin drug therapy. These changes will be compared against doses initiated without genetic data. [...]
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Merck grants license to LabCorp for development of genetic test to predict response of HCV patients
0 Comments | Posted by admin in Gene therapy
Merck announced a non-exclusive license agreement with Laboratory Corporation of America Holdings (LabCorp) for the commercialization of a genetic test that may help predict the response of patients with Hepatitis C virus (HCV) infection to peginterferon alpha-based therapy.
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Iverson Genetic Diagnostics receives CMS approval for warfarin clinical study
0 Comments | Posted by admin in Gene therapy
Iverson Genetic Diagnostics today announced the company has received approval from CMS to conduct a WARFARIN Clinical Study. The two-year (2) study will assess the impact of genetic information in calculating doses and the changes in the rate of adverse events when initiating Warfarin drug therapy. These changes will be compared against doses initiated without [...]
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Nicotinic acetylcholine receptor ?1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy
0 Comments | Posted by admin in Gene therapy
Nicotinic acetylcholine receptor α1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy
Laboratory Investigation advance online publication, July 26, 2010. doi:10.1038/labinvest.2010.135
Authors: Guoqiang Zhang, Alison L Thomas, Amanda L Marshall, Kelly A Kernan, Yanyuan Su, Yi Zheng, Jiro Takano, Takaomi C Saido
& Allison A Eddy (Source: [...]
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Merck signs non-exclusive license agreement with LabCorp for commercialization of genetic test
0 Comments | Posted by admin in Gene therapy
Merck today announced a non-exclusive license agreement with Laboratory Corporation of America Holdings for the commercialization of a genetic test that may help predict the response of patients with Hepatitis C virus infection to peginterferon alpha-based therapy.
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Calibra Medical’s Finesse insulin patch-pen receives FDA clearance for use with Novo Nordisk’s Novolog
0 Comments | Posted by admin in Gene therapy
Calibra Medical announced today it received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Finesse™ insulin patch-pen for up to three-day use with Novo Nordisk’s Novolog® rapid acting insulin. Combining the mealtime therapy-adherence benefits of insulin pumps with the simplicity and affordability of syringes and pens, Calibra’s novel bolus-only patch-pen [...]
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Most men with low-risk prostate cancer receive aggressive treatment
0 Comments | Posted by admin in Gene therapy
Most men who are diagnosed with prostate cancer appear to under undergo aggressive therapy, even if they have a low prostate-specific antigen (PSA) level and low-risk disease, according to a report in the July 26 issue of Archives of Internal Medicine.
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Full face transplant Spaniard displays new look
0 Comments | Posted by admin in Gene therapy
A Spanish man who underwent the world’s first full face transplant appeared before TV cameras Monday for the first time since his surgery, thanking his doctors and the family of the donor.
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QRxPharma reports positive outcome of European Scientific Advice meetings on MoxDuo IR pain therapy
0 Comments | Posted by admin in Gene therapy
QRxPharmareported today positive outcomes of its European Scientific Advice meetings on the development and registration of MoxDuo IR, an immediate release Dual-Opioid™ pain therapy. The Company is currently completing pivotal Phase 3 trials required for filing a New Drug Application (NDA) for MoxDuo IR with the United States Food and Drug Administration (FDA).
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Brainlab launches ExacTrac Infrared Monitoring device for patient positioning during radiation therapy
0 Comments | Posted by admin in Gene therapy
Brainlab announced the availability of ExacTrac® Infrared Monitoring, an add-on device to existing treatment machines for monitoring patient positioning during radiation therapy treatments, at the American Association of Physicists in Medicine (AAPM) Annual Meeting last week.
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CMS Approves Clinical Study of Genetic Test to Predict Patient Response to Leading Anticoagulant Drug Warfarin
0 Comments | Posted by admin in Gene therapy
ATLANTA—-Iverson Genetic Diagnostics today announced the company has received approval from CMS to conduct a WARFARIN Clinical Study. The two-year study will assess the impact of genetic information in calculating doses and the changes in the rate of adverse events when initiating Warfarin drug therapy.
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Genetic Screen for Hepatitis C virus (HCV) Protease Inhibitors
0 Comments | Posted by admin in Gene therapy
A novel in vivo genetic screen for Hepatitis C virus (HCV) Protease Inhibitors has been developed based on the concerted co-expression of a reporter gene, recombinant Hepatitis C virus (HCV) non-structural 3 (NS3) protease and a potential inhibitor…
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Full face transplant Spaniard displays new look
0 Comments | Posted by admin in Gene therapy
Oscar (right), a man who underwent a full-face transplant in April, poses with the Spanish Dr. Joan Barret for the photographers as he appears in public for the first time in a news conference in Barcelona, Spain, Monday, July 26, 2010. (AP) MADRID (AP) – A Spanish man who underwent the world’s first full face [...]
First full face transplant for Spanish man who accidentally shot himself five years ago.
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Aggressive Treatment for Prostate Cancer Is the Norm
0 Comments | Posted by admin in Gene therapy
More than 75% of men diagnosed with low-risk prostate cancer undergo aggressive treatment — either complete removal of the prostate or radiation therapy, according to a new study.
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Magnetic Resonance Imaging-Guided Delivery of Adeno-Associated Virus Type 2 to the Primate Brain for the Treatment of Lysosomal Storage Disorders
0 Comments | Posted by admin in Gene therapy
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)
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Critical Amino Acid Residues Within the ?C31 Integrase DNA-Binding Domain Affect Recombination Activities in Mammalian Cells
0 Comments | Posted by admin in Gene therapy
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)
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Effect of simultaneous silencing of HPV-18 E6 and E7 on inducing apoptosis in HeLa cells.
0 Comments | Posted by admin in Gene therapy
The objective of this investigation was to determine if simultaneous silencing of the human papillomavirus type 18 (HPV-18) E6 and E7 oncogenes using RNA interference (RNAi) would be a potential therapeutic approach against the carcinogenic activity of this virus. Two synthetic double-stranded oligonucleotides, encoding short hairpin transcripts corresponding to HPV-18 E6 and E7 genes, were [...]
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Test could predict which children with T-cell ALL are best candidates for clinical trials
0 Comments | Posted by admin in Gene therapy
A genetic clue uncovered by scientists enables doctors to predict, for the first time, which children with T-cell acute lymphoblastic leukemia (T-ALL) are unlikely to benefit from standard chemotherapy for the disease and should therefore be among the first to receive new treatments in future clinical trials.
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Childhood radiation therapy linked to stillbirths later on
0 Comments | Posted by admin in Gene therapy
Women who had radiation treatment as children have a higher risk of stillbirth and neonatal death, study finds
